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The need to accelerate the transition of
nanotechnology into practical use is gaining increasing
importance. A variety of new nanocomposites material
formulations do already exist but they often do not
correspond to the functional need of biological sciences.
There is still a lack in providing biopharmaceutical
companies with nanoparticles and small series of new
designed multifunctional nanocomposites for biological
applications. Engineered nanoparticles are used in
nanocomposites and coatings for biomedical applications such
as antibacterial implants or catheters, targeted drug
delivery, and drug formulations. Very often the desired
range of applications is restricted due to a limited
availability of nanoparticle materials, their purity, their
re-dispersability (e.g. of agglomerated powders) and costs
(specially for small amounts like pre-series). We are
currently developing new methodologies for development of
custom matrix nanocomposites for biological applications
using silica hybrids, biodegradable polymers and
biocompatible materials. Our initial emphasis is on
generating small amounts of custom matrix nanomaterials by
biomimentics
and ultra short pulsed laser ablation.
This method allows a design of new functionalities of
polymer composites due to nanoparticle derived effects. The
use of a variety of materials and liquids underlies almost
no restrictions. As shown at the example of a bioactive
product, the novel manufacturing route gives access to rapid
nanomaterial generation and variation of properties, e.g.
for pre-clinical studies. |
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