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The need to accelerate the transition of
nanotechnology into practical use is gaining
increasing importance. A variety of new
nanocomposites material formulations do already
exist but they often do not correspond to the
functional need of biological sciences. There is
still a lack in providing biopharmaceutical
companies with nanoparticles and small series of new
designed multifunctional nanocomposites for
biological applications. Engineered nanoparticles
are used in nanocomposites and coatings for
biomedical applications such as antibacterial
implants or catheters, targeted drug delivery, and
drug formulations. Very often the desired range of
applications is restricted due to a limited
availability of nanoparticle materials, their
purity, their re-dispersability (e.g. of
agglomerated powders) and costs (specially for small
amounts like pre-series). We are currently
developing new methodologies for development of
custom matrix nanocomposites for biological
applications using silica hybrids, biodegradable
polymers and biocompatible materials. Our initial
emphasis is on generating small amounts of custom
matrix nanomaterials by biomimentics
and ultra short pulsed laser ablation.
This method allows a design of new functionalities
of polymer composites due to nanoparticle derived
effects. The use of a variety of materials and
liquids underlies almost no restrictions. As shown
at the example of a bioactive product, the novel
manufacturing route gives access to rapid
nanomaterial generation and variation of properties,
e.g. for pre-clinical studies. |
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