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BindiNATM, a controlled release delivery vehicle for target specific delivery of nucleic acid based therapeutics, RNAi, Oligos, gene therapy vectors etc., to provide effective disease specific treatment with minimal side effects.

 
Unique company & technology evaluation

Chikujee Therapeutics’ Nanobindi-NA product engine offers a potential new delivery platforms with a distinct competitive advantage and have identified their key attributes, based on a number of criteria including:

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Proprietary delivery technology
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Applications of the delivery technology within the biopharmaceutical industry
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Management/technical expertise of the delivery specialist
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Competitive edge within the delivery technology sector
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Products in development/approved utilizing the delivery technology
 

Multi-point evaluation and scoring assessment
NanoBindi-NA based drug delivery product engine offers competitive advantage based on a number of parameters, including:
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The technology
NanoBindi-NA delivery platform uses a Multi-stage core-shell architecture as the targeted delivery vehicle (TSDV) for therapeutic nucleic acids. The unique BOSH based polymeric shell protects the nucleic acid from degradation within the body. The targeting ligand (receptor based) ensures active targeting of the TSDV to the desired cell. Once inside the cancer cell, the nucleic acid based therapeutic drug is released, where it is most efficacious.

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The multi-stage shell structure allows choice in terms of route of delivery (oral, parenteral, transdermal, implantable), delivery of Antisense, Ribonucleic acid inhibition (RNAi) , Gene therapy , Nucleoside analogs , Ribozymes, and Aptamers based drugs.

https://www.espicom.com/prodcat.nsf/5116cf707144694a8025702200367a40/7b58097b1844012a80257387005a7fa4/Table_Middle/0.2E92%21OpenElement&FieldElemFormat=gifThe current status of the technology in clinical development

Chikujee is in the preliminary stages of development for conducting pre-clinical studies on number of drug candidates for testing.

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The management team is confident that, based on our technology platform compared to alternative drug delivery systems to technologies under evaluation, we have measurable competitive advantage over competitors

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We intend to strategically align with number of nucleic acid based therapeutics companies in development, strategic alliances, financial position, marketing presence to gain market leadership.

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Drug delivery systems under evaluation, products in development, Commercialisation/ developmental partnerships include candidates from following categories

  • Antisense
  • Ribonucleic acid inhibition (RNAi)
  • Gene therapy
  • Nucleoside analogs
  • Ribozymes, and
  • Aptamers

 

 
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©2008 Chikujee Therapeutics, Inc. All rights reserved.