Surface Engineered Nanoprobes for biomarker monitoring Successful development of ultra-sensitive molecular imaging nanoprobes for the detection of targeted biological objects is a challenging task. The concept of molecular surface engineering is critical for the development of highly uniform and biocompatible nanoparticles with optimized functional properties, which in turn can bring technological innovations to target specific nanoprobing systems.

Chikujee develops ultra-sensitive MR probe systems based on surface-engineered nanoparticles. In particular, molecular probes based on targeted surface engineered nanobindis (SENB), with strong magnetic properties, will have considerably enhanced sensitivity for cancer cell detection and also make the in vivo imaging of small tumors possible. By using appropriate cancer targeting molecules, the ultra-sensitive MR detection of various types of cancers may be possible. Ultimately, high-performance magnetic nanoprobing systems could play a pivotal role in the realtime visualization of other biological events, such as cell trafficking, cancer metastasis, cellular signaling and interactions at the molecular and cellular level.