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- Brightly glowing nanoparticle with
Core-Shell Architecture
NanoBindisTM are fluorescent
nanoparticles that have a fluorescent dye as
a core in a silica shell to ensure
photostability, low cytotoxicity and high
sensitivity for biological applications.
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The Multifunctional NanoBindis with core-shell architecture
have been customized for four major classes of therapeutic
payloads:
BindiPRTM, a controlled release delivery
vehicle for target specific delivery of protein based
therapeutics to produce a more effective drug for treatment
with minimal side effects.
BindiNATM,
a controlled release delivery vehicle for target specific
delivery of nucleic acid based therapeutics, RNAi, Oligos,
gene therapy vectors etc., to provide effective disease
specific treatment with minimal side effects.
BindiSMTM
for the cell specific delivery of small molecules like
chemotherapy agents to the target site
BindiGPTM
for the cell specific delivery of general purpose
therapeutic agents to target tissues.
This innovative approach will enable personalized management
of cancer and provide an integrated protocol for diagnosis
and follow up that is so important in management of cancer
in patients. It will radically change the way we diagnose,
treat and prevent cancer to help meet the goal of
eliminating suffering and death from cancer.
Based on multifunctional NanoBindis, Chikujee therapeutics
has developed two product engines for creating next
generation blockbusters.
1.
Rasayana:
Multifunctional NanoBindi product engine for small
molecules, proteins and nucleic acid based therapeutics.
2.
NanoRISC:
Multifunctional NanoBindi product engine for SiRNA
therapeutics
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