Technology-Product Engines for Next Generation Blockbusters

MFNB The Technology

Chikujee Therapeutics has developed an innovative technology platform that uses multifunctional NanoBindi™ for integrated disease management. Multifunctional nanoparticles have tremendous potential to make important contributions in cancer prevention, detection, diagnosis, imaging and treatment. It can target a tumor, carry imaging capability to document the presence of tumor, sense patho-physiological defects in tumor cells, deliver therapeutic genes or drugs based on tumor characteristics, respond to external triggers to release the agent and document the tumor response and identify residual tumor cells.

Chikujee’s proprietary multifunctional NanoBindi™ has following unique characteristics:

	1. Non-invasive, ultrasensitive detection of cancer cells/tissue
	2. Cell-specific delivery of therapeutic drug without side effects
	3. In Vivo, at-site clinical monitoring of therapeutics efficacy of the drug by patient friendly non-invasive methods
	4. Non-toxic, non-immunogenic nanoparticles
	5. Simple, cost-effective manufacturing process that is easy to scale up
	6. Nanoparticles with high zeta potential that are electrically stabilized and confer excellent stability, i.e. the solution or dispersion will resist aggregation.

Based on multifunctional NanoBindis, Chikujee therapeutics has developed two product engines for creating next generation blockbusters.

1. Rasayana: Multifunctional NanoBindi product engine for small molecules, proteins and nucleic acid based therapeutics.

2. NanoRISC: Multifunctional NanoBindi product engine for SiRNA therapeutics